Anti-tuberculosis Drug-induced Liver Injury (ATLI) Effects

Hostile to tuberculosis Drug-initiated Liver Injury (ATLI) Effects Unique Tuberculosis (TB) is world’s deadliest transferable sickness, with 9 million occurrence cases and 1.5 million passings all around in 2013. The majority of the instances of TB were accounted for from Asian (56%), and African (29%) landmasses. In Saudi Arabia the yearly occurrence pace of TB ran somewhere in the range of 14 and 17/100,000. Two territories, Makkah and Jazan demonstrated the most noteworthy rate around 20/100,000 in the course of the most recent multi decade. Jazan locale indicated more than twofold the frequency pace of TB contrasted with rest of the Southern area. Jazan share fringe with Yemen, and gets numerous illicit settlers. Studies indicated that non-Saudi Arabians had 2-3 times higher occurrence of TB than Saudi national. The huge number of Non-Saudis originated from nations with high frequency of TB, for example, Bangladesh, Pakistan, India, Indonesia, Philippines, Yemen, Ethiopia, Somalia, Chad, Nigeria and other African nations. The dynamic TB patients can be dealt with securely and successfully through the legitimately watched treatment methodology (DOTS). Spots is a short course of standard enemy of TB treatment which comprise of taking medication blends of Isoniazid, Rifampicin, Pyrazinamide, Ethambutol and Streptomycin for 6â€9 months. The medication isoniazid, rifampicin and pyrazinamide can possibly instigate liver damage.This hostile to tuberculosis sedate incited liver injury (ATLI) ranges from mellow to serious structures, and can even be deadly. The occurrence of ATLI during standard enemy of TB treatment extend from 2.0% to 28.0% as per various populaces. In addition, ATLI lessen the adequacy of hostile to TB treatment, as they may cause treatment disappointment, backslide and sedate opposition which could altogether decrease the impacts of TB control. As far as we could possibly know, there is no known distributed information on the rate of hostile to tuberculosis sedate prompted liver injury (ATLI) and hazard fact ors from Saudi populace. Distinguishing proof of patients at expanded hazard for ATLI is significant in light of the fact that hepatotoxicity causes huge dreariness and mortality and may require adjustment of the helpful routine. The point of this investigation will to assess the frequency of ATLI and the hazard factors related with hostile to TB treatment. The discoveries of this investigation will permit us to upgrade TB treatment, checking and control of the TB in KSA. Presentation Tuberculosis (TB) is world’s deadliest transferable ailment, with 9 million occurrence cases and 1.5 million passings all around in 2013 [1]. The vast majority of the instances of TB were accounted for from Asian (56%), and African (29%) mainlands [1]. In Saudi Arabia the yearly rate pace of TB extended somewhere in the range of 14 and 17/100,000 [2]. Two areas, Makkah and Jazan indicated the most elevated occurrence around 20/100,000 in the course of the most recent multi decade [2]. Jazan locale indicated more than twofold the frequency pace of TB contrasted with rest of the Southern area. Jazan share outskirt with Yemen, and gets numerous unlawful migrants. Studies demonstrated that non-Saudi Arabians had 2-3 times higher frequency of TB than Saudi national. [3]. The huge number of Non-Saudis originated from nations with high frequency of TB, for example, Bangladesh, Pakistan, India, Indonesia, Philippines, Yemen, Ethiopia, Somalia, Chad, Nigeria and other African nations. Patients with dynamic TB illness can be dealt with securely and successfully through the straightforwardly watched treatment methodology (DOTS) which began in 2000. Spots is a short course of standard enemy of TB treatment which comprise of taking medication blends of Isoniazid, Rifampicin, Pyrazinamide, Ethambutol and Streptomycin for 6â€9 months [4]. These medications successfully murders the microorganisms however it incited hepatotoxicity known as against tuberculosis tranquilize prompted liver injury (ATLI) [5.tostmann 2008]. The ATLI ranges from gentle to extreme structures, and can even be lethal. The rate of ATLI during standard enemy of TB treatment extend from 2.0% to 28.0% as indicated by various populaces. [5,6]. The occurrence is higher in the creating nations (8% to 39%), contrasted with created nations (3%â€4%) (7-11). Also, ATLI diminish the viability of hostile to TB treatment, as they may cause treatment disappointment, backslide and tranquilize opposition which could essentially decrease the impacts of TB control. [5,6]. Many hazard factors have been involved for ATLI. These incorporate more seasoned age, female sexual orientation, poor wholesome status, previous liver ailment, high liquor consumption, hepatitis B, lack of healthy sustenance, hypoalbuminaemia and propelled TB (12-16). Improper utilization of medications, acetylator status, and as of late, immunogenetic factor, have additionally been embroiled (17,18). Diseases with hepatitis C infection and human immunodeficiency infection (HIV) have likewise been said to build the hazard (19). It is imperative to comprehend the hazard components of ATLI, so as to distinguish the unfavorable occasions prior and convey convenient intercession. The recognizable proof of high-hazard patients would be helpful to permit early recognition of hepatotoxicity and lessen the dreariness and mortality of this condition. Subsequently we plan this examination to distinguish the hazard factors related with against tuberculosis medicate prompted liver injury in patients who get hostile to TB treatment. As far as we could possibly know, there is no known distributed information on the frequency of against tuberculosis sedate actuated liver injury (ATLI) and hazard factors from Saudi populace. The point of this investigation will to assess the occurrence of ATLI and the hazard factors related with hostile to TB treatment. The discoveries of this investigation will permit us to upgrade TB treatment, observing and control of the TB in KSA. 2. Task OBJECTIVES This investigation expected to appraise the occurrence and hazard variables of against tuberculosis Drug Induced Liver Injury (ATLI) in understanding getting hostile to TB treatment in Jazan populace. 1. To evaluate the rate of strange liver capacity tests (LFTs) in quiet accepting enemy of TB treatment. 2. To distinguish the hazard factors related with hostile to tuberculosis Drug Induced Liver Injury (ATLI) in persistent accepting enemy of TB treatment. Survey of Literature Frequency The primary line drugs used to treat TB were isoniazid (INH), rifampicin (RIF), pyrazinamide (PZY) and ethambutol (EMB). A large portion of the TB patients endure the medications however some create hepatotoxicity known as hostile to tuberculosis tranquilize prompted liver injury (ATLI). [Forget 2006].The ATLI ranges from mellow to extreme structures, and can even be lethal. Information from the writing shows that the rate of ATLI is 3.0% in Canada (Asia populace represented 42%)[Yee 2003], China 2.5% [Shang 2011], 5.0% in Hong Kong[ Chang 2008], 5.3% in Singapore[teleman 2002], 16.1% in Taiwan [Huang 2003], 9.7% in Malaysia [Marzuki 2008],36% in Japan [Ellard 1978], 8-36 percent in India [Parthasarthy 1986, Mehta 1990], 13% Iran [Baghaei]. The danger of creating ATLI was fivefold for hepatitis C patients, fourfold for HIV positive patients, and 14 overlay for patients co-tainted with hepatitis C and HIV [Ungo 1998]. The occurrence is higher in the creating nations (8% to 39%), contrasted with created nations (3%â€4%) (7-11). In addition, ATLI decrease the viability of hostile to TB treatment, as they may cause treatment disappointment, backslide and medicate obstruction which could fundamentally lessen the impacts of TB control. [5,6]. Meaning of ATLI The measures for the conclusion of ATLI without indications is rise of transaminases up to multiple times the maximum furthest reaches of ordinary (ULN) and within the sight of manifestations up to multiple times the ULN or double the ULN of bilirubin in the blood [Saukkonen 2006]. System of harmfulness Among Isoniazid, rifampicin, pyrazinamide and ethambutol, the initial three medications have the potential for hepatotoxicity with pyrazinamide (PZA) being the most hepatotoxic followed by isoniazid (INH) and rifampicin.[Yee]Rifampicin joined with PZA is more hepatotoxic than with INH.[ Jasmer 2002]Pyrazinamide contributes altogether to intense liver disappointment [ Durand 1995].The most significant unfavorable impacts of isoniazid are hepatic harmfulness and conceivably deadly medication prompted hepatitis[Nolan 1999], particularly when related with rifampicin. The recurrence of event of isoniazid-related hepatitis relies upon age. Different components connected to an inclination to isoniazid-related hepatotoxicity incorporate liquor misuse, utilization of unlawful medications and a past history of liver sickness. Clinical highlights ATLI for the most part occur in the initial 2 months of treatment however it might occur whenever during the treatment time frame. Clinical and biochemical highlights of ATLI are hard to separate structure viral hepatitis [Mitchell 1976]. The signs and side effects of ATLI are jaundice, stomach torment, sickness, retching and Weakness. Hazard factors for ATLI Many hazard factors have been ensnared for ATLI. These incorporate more established age, female sex, poor nourishing status, prior liver sickness, high liquor consumption, hepatitis B, lack of healthy sustenance, hypoalbuminaemia and propelled TB (12-16). Unseemly utilization of medications, acetylator status, and as of late, immunogenetic factor, have additionally been embroiled (17,18). Contaminations with hepatitis C infection and human immunodeficiency infection (HIV) have likewise been said to build the hazard (19).

Secure Sockets Layer in Security Technology

Secure Sockets Layer in Security Technology SSL (Secure Sockets Layer) the most broadly utilized and most impressive measure in security innovation for making a scrambled connection between the Web Server internet browsers. On the off chance that the connection is encoded, they use https convention. Secure repository Layer (SSL) and Transport Layer Security (TLS) is the convention above TCP, which can ensure clients secrecy when they sending information from a client side to a web server; this is a significant convention because of the augmentation of Internet. Truth be told, it is far to make the SSL/TLS convention completely . Anyway there are still imperfection and issues during the advancement of SSL/TLS, and we can't deny that theremaybe some other potential security opening in the most recent adaptation. consecutive assault is lethal for both the client and the organization in utilizing these conventions to set up a sheltered channel to move data. This article will present three normal assaults: Cipher suite rollback ass ault, portrayal rollback assault and secret phrase special case in SSL/TLS channel.[1]. As the web and World Wide web become normal, it is important to consider the framework security. this can be on the grounds that the plaintext moving through the web is decoded, it is for wafer or programmer, even a client with none programming data, to catch the message and adjust it. The best approach to safeguard individual protection, and an approach to ensure a safe on-line trade.. These square measure the test for information Technology. SSL/TLS will made a genuine secure channel among server and customer which may code the plaintext, at that point the outsider who catch the message can not uncover the primary message without unscramble it.[1]. The Secure Sockets Layer (SSL) could be a procedure for giving security to web essentially based applications. it is intended to make utilization of TCP to create a solid start to finish secure assistance. SSL isn't one convention anyway rather two layers of conventions as outlined It will be seen that one layer utilizes TCP straightforwardly. This layer is comprehended on the grounds that the SSL Record Protocol and it gives fundamental security administrations to different higher layer conventions. an independent convention that makes utilization of the record convention is that the hypertext language (HTTP) convention. Another 3 more significant level conventions that likewise make utilization of this layer are a piece of the SSL stack.SSL incorporate two stages: handshaking and data move. all through the handshaking strategy, the buyer and server utilize an open key encoding calculation to work out mystery key boundaries, during the data move technique, each side utilize the way to record and interpret progressive data transmissions[1]. SSL (Secure Sockets Layer) is an innovation to scramble interchanges between the client and the web server. It assists with forestalling programmer assaults that depend on listening stealthily. At the point when you utilize a website page that is ensured by SSL, you see a lock symbol that guarantees you that the page is secure. 3.1 Is the site truly secure with SSL? No. SSL makes sure about the system correspondence connect as it were. In spite of the fact that this is a significant security layer for delicate applications, most assaults on sites are not really done along these lines. Most assaults on sites are really done in one of the accompanying ways: The server is assaulted straightforwardly. SSL doesn't shield you from this. Or maybe, you have to have a decent IT security strategy to ensure your server. The client is assaulted straightforwardly, either by contaminating their PC with malware, or by utilizing phishing to take their passwords. SSL doesn't shield you from this, either. To shield your own PC from this, you have to utilize a decent enemy of infection program, and use heaps of presence of mind and a modest quantity of distrustfulness when on the Internet. Nonetheless, it is ridiculous to expect that all the PCs of the entirety of your site guests will be enough ensured. As it were, SSL does almost no to keep the site from being hacked. It just keeps outsiders from tuning in to interchanges between the client and the site. All things considered, when is SSL essential to have? In the event that you are transmitting touchy private information over the web, SSL is a significant extra security layer. In spite of the fact that listening in might be a less basic type of assault on the site, there is no explanation not to ensure against it if the results are not kidding. In spite of the fact that the hazard to the site may not be that incredible, the hazard to singular clients might be noteworthy now and again. For example, any client getting to your site from an open wireless association, (for example, at a bistro) can be spied on reasonably effectively by different clients at a similar area. Meddlers can perceive what is composed into structures on non-SSL locales, so the dangers will rely upon what sorts of structures you have. The most clear high-hazard structure is your login structure, which requests username and secret key. A meddler can possibly get these login qualifications and afterward sign in as that client. How hazardous or risky that is relies upon what individual data the busybody can acquire, or what hurt they can cause with this data. Regardless of whether the hazard is low with respect to your site, you ought to likewise look at that as some clients will re-use passwords on numerous sites, so the hazard may reach out to destinations and circumstances that are outside your ability to control. What sort of delicate private information needs assurance? Private information will be data that should just be known to you (the site proprietor) and the client. The most evident model is charge card numbers. In the event that you redistribute your Mastercard handling to an outside internet business door, the exchanges are secured by your web based business suppliers SSL. Including SSL your site isn't vital for this situation. Passwords are the following most clear thing to ensure, as noted previously. On the off chance that you don't have an enrollment or open client base, at that point your very own administrator passwords might be the main ones you have to consider. In the event that you don't do site organization from open wifi systems, at that point this is certainly not a significant concern. Note that individual data, for example, names, email addresses, telephone numbers, and postage information are not private. This is data that is intended to be imparted to other people. SSL doesn't generally secure data that is as of now openly accessible in increasingly available arrangements, for example, the telephone directory. (Nonetheless, you do require a decent security strategy when putting away and utilizing people groups individual data, to guarantee your clients why you need their own data, and what you mean to utilize it for. This is for the most part since certain associations have a past filled with selling their databases of individual data against the desires of their customers. SSL doesn't help with this, be that as it may.) There is an ill defined situation between private information (which ought to be known distinctly to you and the client), and individual information (which is known and utilized by numerous others). Singular bits of individual information may not be a serious deal, yet on the off chance that you gather enough close to home information, wholesale fraud may turn into a conceivable danger. Unique record or character numbers (SSN, SIN, drivers permit, social insurance, or identification numbers for instance), alongside birth dates, normal security questions (eg. moms birth name, names of relatives), and data of that nature may by and large include a character that could be taken for loathsome purposes. The a greater amount of this kind of data you gather, the more SSL may be a beneficial expansion to your security strategy. The Secure Sockets Layer (SSL) Protocol was embraced by Netscape in 1994 as a reaction to the developing worry over Internet security. Netscapes objective was to make a scrambled information way between a customer and a server that was stage or OS freethinker. Netscape likewise grasped to exploit new encryption plans, for example, the ongoing appropriation of the Advanced Encryption Standard (AES), considered more secure than Data Encryption Standard (DES). For sure, by June 2003, the US Government regarded AES sufficiently secure to be utilized for characterized data. 4.1 Birth of SSL At the point when internet browser built up their applications software engineer, they found that in the dealings between web server and internet browser, there ought to be some security approach to watch the message shifted back and forth among customer and server, especially for a couple of business poppers. From the outset, internet browser set up some mystery writing in their applications. Notwithstanding, they found that the mystery composing didnt support non-HTTP applications. SSL (Secure Sockets Layer) convention was built up that is essentially over the TCP (Transmission Control Protocol) to shape this security.[1]. 4.2 Development of SSL During the past barely any years, SSL grew quickly, because of theres constantly some protected gaps and a couple of past forms of SSL can't hinder assailant to listening stealthily or capture appropriately. for instance, Version 3.0 of SSL was bound to right a blemish in past variants 2.0, the figure suite rollback assault, whereby Associate in Nursing contestant may get the gatherings to embrace a powerless cryptosystem.[1]. TLS was released because of the net communitys requests for a normalized convention. The IETF gave a setting to the new convention to be unmistakably talked about, and enlivened designers to give their contribution to the convention. The Transport Layer Security (TLS) convention was released in January 1999 to make a standard for private interchanges. The convention permits customer/server applications to convey in an exceedingly approach that is intended to forestall eavesdropping,tampering or message forgery.According to the conventions makers, the objectives of the TLS convention square measure crypto graphical security, capacity, extensibility, and relative strength. These objectives square measure accomplished through usage of the TLS convention on two levels: The TLS Record convention and furthermore the TLS handshake convention. TLS Record Protocol The TLS Record convention arranges a private, solid association among theclient and furthermore the serv

Case Study of a Drug Addict

CED 322: Case Study For the situation of the multi year-old female customer, I would start my appraisal of her by endeavoring to diminish her present condition of uneasiness. My first objective is permit her to have a sense of security and agreeable when she enters my office. I need her to realize that my office is a place of refuge from anything that makes her backslide. Moreover, by saluting her choice to look for treatment I can make early walks in creating trust and affinity from the start.Once the customer and I invest some energy assessing her biography, I would request that her total the SASSI-3 to give me an even point of view of her general battle with cocaine and heroin misuse. In spite of the fact that I’ve been given some foundation data on the client’s past history of misuse, I feel that the SASSI-3 can give me some knowledge to propensities and qualities she created from her family and way of life growing up. Since I have some data about her initial utiliz ation of liquor, I would likewise regulate a MAST which could give me some knowledge on her reliance with alcohol.I would have the option to all the more likely see how liquor assumes a job in her utilization of heroin and cocaine. When I can decide how they correspond I can then precisely analyze her and lead to an increasingly fruitful treatment system. From the present data I would determine this customer to have Cocaine and Opioid-Induced Mood Disorder (292. 84). The customer reports that she backslides when she wants to feel â€Å"numb† which reveals to us her feelings and sentiments are essential factors that impact her addictive behavior.Also, her fixation is extreme to the point that she guarantees that she utilizes now and again for reasons unknown by any stretch of the imagination. Since she is contrite and dreadful of her life, I feel that she is scanning for the correct treatment to free herself of this dangerous fixation. She wants to change yet needs the will to change. I would concentrate on her regular everyday practice, taking out the pieces of her day that include musings or thoughts that lead to utilizing heroin and cocaine. I would suggest that she utilize the 12 stage program and gathering treatment as better approaches to manage her towards recovery.Since she utilizing these substances in private, I feel she might profit by other people who know and feel indistinguishable battles from she does. This would permit her to not feel alone in her recuperation and carry a feeling of responsibility to keep from backslide. I would screen her advancement in the 12 stage program and urge her to quietly finish each progression. I’m putting together my treatment system with respect to trust. So as to wipe out her dread and tension alongside her dependence through these screens and techniques, she should be happy to confide in herself consistently.

Human Resources Management Aspects Essay Example | Topics and Well Written Essays - 2250 words

HR Management Aspects - Essay Example Equivalent Employment Opportunities and governmental policy regarding minorities in society are terms that individuals normally use in their day by day lives without understanding their genuine significance, the distinction among them, and their application in human asset the board. Equivalent business openings and governmental policy regarding minorities in society are the rules that were set by the legislature and target guaranteeing reasonableness in work environments since they preclude any type of segregation. I have seen individuals treat each other distinctively due to their diverse nationality, race, ethnicity, or sexual orientation. Learning this course was significant since I presently comprehend that Equal Employment Opportunity is a guideline, which restricts segregation of any sort whether racial, sexual orientation based or ethic based, against any worker or people looking for business (Ulrich, 2005). Without this standard, clearly the recruiting procedure, advancements , access to proficient improvement openings would be looked by bias. Realizing what governmental policy regarding minorities in society is was another critical viewpoint in this unit. Governmental policy regarding minorities in society is a cure or a standard used to deal with or address past instances of segregation. Governmental policy regarding minorities in society along these lines guarantees that associations resolve to beat segregation, which begins with tending to past discriminative activities and look to wipe out all hindrances that should confine or forestall proficient improvement of any person. The governmental policy regarding minorities in society was ordered to guarantee associations set up measures to improve the interest. of females, people with inability just as minority gatherings. For instance, I have seen a few associations promote certain occupations in ladies magazines to guarantee that they increment the odds of ladies being the fundamental candidates. It's anything but another marvel to know about situations where workers have been dealt with unfairly due to their race, conjugal status, handicap, transgender status, sexuality, or different factors, for example, carer’s obligations. It was fascinating discovering that the above activities are unlawful. Be that as it may, it's anything but another wonder to know about situations where a business or supervisor who sacked a representative, for instance, since she was pregnant or in light of the fact that she or he was impaired and couldn't deal with specific errands. This isn't right since ones shading, sexual orientation or genuineness doesn't show or even decide their ability. Everybody should in this manner be given equivalent chance to affirm their latent capacity (Ulrich, 2005). EEO expects bosses to abstain from utilizing specific models to extend employment opportunities or advancements to specific gatherings of individuals especially the minority. In any case, governmental policy regarding minorities in society is results situated and is intended to address underutilization of minority gatherings, which frequently result if work, advancement, and profession improvement openings are given similarly without thinking about assorted variety. This course presented me to the difficulties looked by chiefs and managers during the employing procedure since all their

Late-2000s recession Essay Example for Free

Late-2000s downturn Essay European Tour Operators have figured out how to accomplish a solid situation in the travel industry. The two greatest ones, TUI Travel and Thomas Cook, have a huge piece of the overall industry. Be that as it may, in the last piece of the decade, somewhere in the range of 2007 and 2010 the business has encountered a downturn on account of the violent condition which was made new dangers and altered the serious powers. Political: Tax collection Policies on movement strategies by various nations largy affects the travel industry, governments give a few appropriations and assessment exclusions in their nations so as to advance the correct the travel industry. Visas into specific nations can likewise make individuals quit going there as degenerate nations can charge a lot of cash to pick up them. Political shakiness can not just influence the nation wherein it is yet in addition neighboring nations. The equivalent likewise happens when psychological oppressor acts occur on a nation or are from a nation. Practical: Globalization of movement organizations and carriers has implied that numerous nations can offer types of assistance that they couldn't before do to social information. With organizations being worldwide there are likewise economies of scale to be picked up. TUI’s vertical and flat incorporation makes them exceptionally serious and they offer types of assistance over all holidaying encounters. Trade rates region huge part to the measure of vacationers going from every nation. On the off chance that one nations cash gets more vulnerable than others it is bound to turn into a vacation goal because of an anticipated ‘value for money’. This influences the organization less as they have a more grounded position than the client in that they can charge the client relying upon the nation with the more grounded cash. The downturn has likewise caused a few issues inside the business as there have been a few organizations that have not been effective. TUI figured out how to make it

Tips for a beautiful life!

Tips for a beautiful life! This story contains some “tips” that may bring you a beautiful life. Read them, live by them more fully, and I promise you will experience a beautiful life!Take a 10-30 minute walk every day and while you walk, smile.Sit in silence for at least 10 minutes each day.When you wake up in the morning complete the following statement, “My purpose is to … today.”Live with the 3 E’s: Energy, Enthusiasm, Empathy, and the 3 F’s: Faith, Family, Friends.Spend more time with people over the age of 70 and under the age of 6.Dream more while you are awake.Try to make at least three people smile each day.Realize that life is a school and you are here to learn, pass all your tests. Problems are simply part of the curriculum that appear and fade away like algebra class but the lessons you learn will last a lifetime.Smile and laugh more. It will keep the energy vampires away.Life isn’t fair, but it’s still good.Life is too short to waste time hating anyone.Don’t take yourself so ser iously. No one else does.You don’t have to win every argument. Agree to disagreements.Make peace with your past, so it won’t mess up the present.Don’t compare your life with others’. You have no idea what their journey is all about.Burn the candles, use the nice sheets. Don’t save it for a special occasion. Today is special.No one is in charge of your happiness except you.Forgive everyone for everything.What other people think of you is none of your business.Time heals almost everything. Give time, time.However good or bad a situation is, it will change.Your job won’t take care of you when you are sick. Your friends will stay in touch.Get rid of anything that isn’t useful, beautiful, or joyful.The best is yet to come… Believe.No matter how you feel, get up, dress up, and show up.Do the right thing!Call your family often.Each night before you go to bed complete the following statements: “I am thankful for…” “Today I accomplished…Remember that you are too bl essed to be stressed.Enjoy the ride. Remember that this is not Disney World and you certainly don’t want a fast pass. Make the most of it and enjoy the ride.Author Unknown Story submitted by John C.  

Tips for a beautiful life!

Tips for a beautiful life! This story contains some “tips” that may bring you a beautiful life. Read them, live by them more fully, and I promise you will experience a beautiful life!Take a 10-30 minute walk every day and while you walk, smile.Sit in silence for at least 10 minutes each day.When you wake up in the morning complete the following statement, “My purpose is to … today.”Live with the 3 E’s: Energy, Enthusiasm, Empathy, and the 3 F’s: Faith, Family, Friends.Spend more time with people over the age of 70 and under the age of 6.Dream more while you are awake.Try to make at least three people smile each day.Realize that life is a school and you are here to learn, pass all your tests. Problems are simply part of the curriculum that appear and fade away like algebra class but the lessons you learn will last a lifetime.Smile and laugh more. It will keep the energy vampires away.Life isn’t fair, but it’s still good.Life is too short to waste time hating anyone.Don’t take yourself so ser iously. No one else does.You don’t have to win every argument. Agree to disagreements.Make peace with your past, so it won’t mess up the present.Don’t compare your life with others’. You have no idea what their journey is all about.Burn the candles, use the nice sheets. Don’t save it for a special occasion. Today is special.No one is in charge of your happiness except you.Forgive everyone for everything.What other people think of you is none of your business.Time heals almost everything. Give time, time.However good or bad a situation is, it will change.Your job won’t take care of you when you are sick. Your friends will stay in touch.Get rid of anything that isn’t useful, beautiful, or joyful.The best is yet to come… Believe.No matter how you feel, get up, dress up, and show up.Do the right thing!Call your family often.Each night before you go to bed complete the following statements: “I am thankful for…” “Today I accomplished…Remember that you are too bl essed to be stressed.Enjoy the ride. Remember that this is not Disney World and you certainly don’t want a fast pass. Make the most of it and enjoy the ride.Author Unknown Story submitted by John C.